Radical Prostatectomy excluded studies

Excluded references and reasons for exclusion

E1: Not adult patients
with prostate cancer following prostatectomy using open or laparoscopic
radicalprostatectomy including computer-assisted laparoscopic radical
prostatectomy (CALP)

1.         Charlton S, Cyna Allan M, Middleton P,
Griffiths James D (2010) Perioperative transversus abdominis plane (TAP) blocks
for analgesia after abdominal surgery. Cochrane Database of Systematic Reviews,
DOI: 10.1002/14651858.CD007705.pub2,

2.         Dowling AJ, Tannock IF (1998) Systemic
treatment for prostate cancer. Cancer Treatment Reviews 24:283-301

3.         Edomwonyi NP, Omoifo CE (2008)
Increasing use of regional anaesthesia for prostatectomy – University of Benin
Teaching Hospital experience. Southern African Journal of Anaesthesia and
Analgesia 14:13-17

4.         Fredman B, Olsfanger D, Flor P,
Jedeikin R (1996) Ketorolac does not decrease postoperative pain in elderly men
after transvesical prostatectomy. Canadian Journal of Anaesthesia 43:438-441

5.         Fredman B, Zohar E, Ganim T, Shalev M,
Jedeikin R (1998) Bupivacaine infiltration into the neurovascular bundle of the
prostatic nerve does not improve postoperative pain or recovery following
transvesical prostatectomy. The Journal of urology,

6.         Hendolin H, Mattila MAK, Poikolainen E
(1981) The effect of lumbar epidural analgesia on the development of deep vein
thrombosis of the legs after open prostatectomy. Acta Chirurgica Scandinavica

7.         Hendolin H, Penttilä IM (1982) Liver
enzymes after retropubic prostatectomy in patients receiving continuous lumbar
epidural analgesia or general anaesthesia. Annals of Clinical Research,

8.         Lee YY, Muchhal K, Chan CK (2003)
Levobupivacaine versus racemic bupivacaine in spinal anaesthesia for urological
surgery. Anaesthesia and Intensive Care,

9.         Lee YY, Muchhal K, Chan CK, Cheung AS
(2005) Levobupivacaine and fentanyl for spinal anaesthesia: a randomized trial.
European Journal of Anaesthesiology,

10.       Patel D, Janardhan Y, Merai B, Robalino
J, Shevde K (1990) Comparison of intrathecal meperidine and lidocaine in endoscopic
urological procedures. Canadian journal of anaesthesia = Journal canadien

11.       Rees J, Patel B, Macdonagh R, Persad R
(2004) Cryosurgery for prostate cancer. BJU International 93:710-714

12.       Skretting P, Vaagenes P, Sundnes KO,
Edström HH, Lind B (1984) Subarachnoid anaesthesia: comparison of hyperbaric
solutions of bupivacaine and amethocaine. British Journal of Anaesthesia,

E2: Not a comparison of two or more interventions (analgesia, anesthesia, operative
techniques) affecting postoperative pain

1.         Grass JA, Sakima NT, Valley M, Fischer
K, Jackson C, Walsh P, Bourke DL (1993) Assessment of ketorolac as an adjuvant
to fentanyl patient-controlled epidural analgesia after radical retropubic
prostatectomy. Anesthesiology 78:642-648

2.         Hurtes X, Roupret M, Vaessen C, Pereira
H, Faivre D’Arcier B, Cormier L, Bruyere F (2012) Anterior suspension combined
with posterior reconstruction during robot-assisted laparoscopic prostatectomy
improves early return of urinary continence: A prospective randomized
multicentre trial. BJU International 110:875-883

3.         Kier L (1974) Continuous epidural
analgesia in prostatectomy: comparison of bupivacaine with and without
adrenaline. Acta Anaesthesiologica Scandinavica:1-4

4.         Magheli A, Knoll N, Lein M, Hinz S,
Kempkensteffen C, Gralla O (2011) Impact of fast-track postoperative care on
intestinal function, pain, and length of hospital stay after laparoscopic
radical prostatectomy. Journal of Endourology 25:1143-1147

5.         Nosnik IP, Gan TJ, Moul JW (2007) Open
radical retropubic prostatectomy 2007: The true minimally invasive surgery for
localized prostate cancer? Expert Review of Anticancer Therapy 7:1309-1317

E3: No reporting of at least one of the following outcomes: pain assessment, required
analgesic or adverse events

1.         Ficarra V, Cavalleri S, Novara G,
Aragona M, Artibani W (2007) Evidence from Robot-Assisted Laparoscopic Radical
Prostatectomy: A Systematic Review. European Urology 51:45-56

2.         Fracalanza S, Ficarra V, Cavalleri S,
Galfano A, Novara G, Mangano A, Plebani M, Artibani W (2008) Is robotically
assisted laparoscopic radical prostatectomy less invasive than retropubic
radical prostatectomy? Results from a prospective, unrandomized, comparative
study. BJU International 101:1145-1149

3.         Goldstraw MA, Patil K, Anderson C,
Dasgupta P, Kirby RS (2007) A selected review and personal experience with
robotic prostatectomy: Implications for adoption of this new technology in the
United Kingdom. Prostate Cancer and Prostatic Diseases 10:242-249

4.         Hendolin H, Alhava E (1982) Effect of
epidural versus general anaesthesia on peroperative blood loss during
retropubic prostatectomy. International Urology and Nephrology,

5.         Jenkins J, Fox J, Sharwood-Smith G
(1983) Changes in body heat during transvesical prostatectomy. A comparison of
general and epidural anaesthesia. Anaesthesia,

6.         Kaukinen S, Kaukinen L, Eerola R (1980)
Epidural anaesthesia with mixtures of bupivacaine-lidocaine and
etidocaine-lidocaine. Annales Chirurgiae et Gynaecologiae 69:281-286

7.         O’Connor PJ, Hanson J, Finucane BT
(2006) Induced hypotension with epidural/general anesthesia reduces transfusion
in radical prostate surgery. Canadian Journal of Anesthesia 53:873-880

8.         Shir Y, Raja SN, Frank SM, Brendler CB
(1995) Intraoperative blood loss during radical retropubic prostatectomy:
Epidural versus general anesthesia. Urology 45:993-999

9.         Tikuisis R, Miliauskas P, Samalavicius
NE, Zurauskas A, Sruogis A (2009) Epidural and general anesthesia versus
general anesthesia in radical prostatectomy. Medicina (Kaunas, Lithuania) 45:772-777

10.       Wagner AA, Varkarakis IM, Link RE,
Sullivan W, Su LM (2006) Comparison of surgical performance during laparoscopic
radical prostatectomy of two robotic camera holders, EndoAssist and AESOP: A
pilot study. Urology 68:70-74

E4: Neither systematic review (of RCT/CCT) nor RCT/CCT

1.         Albertsen PC (2005) General versus
spinal anesthesia in patients undergoing radical retropubic prostatectomy:
results of a prospective, randomized study. The Journal of urology 174:931

2.         Bhayani SB, Pavlovich CP, Hsu TS,
Sullivan W, Su LM (2003) Prospective comparison of short-term convalescence:
Laparoscopic radical prostatectomy versus open radical retropubic
prostatectomy. Urology 61:612-616

3.         Ficarra V, Novara G, Artibani W,
Cestari A, Galfano A, Graefen M, Guazzoni G, Guillonneau B, Menon M, Montorsi
F, Patel V, Rassweiler J, Van Poppel H (2009) Retropubic, Laparoscopic, and
Robot-Assisted Radical Prostatectomy: A Systematic Review and Cumulative
Analysis of Comparative Studies. European Urology 55:1037-1063

4.         Lepor H (2004) Radical prostatectomy:
Status and opportunities for improving outcomes. Cancer Investigation 22:435-444

5.         Menon M, Shrivastava A, Tewari A (2005)
Laparoscopic radical prostatectomy: Conventional and robotic. Urology 66:101-104

patient population does not comprise at least 80% prostatectomies or the
statistical analyses are separately calculated and presented

1.         Atanassoff PG, Hartmannsgruber MWB,
Thrasher J, Wermeling D, Longton W, Gaeta R, Singh T, Mayo M, McGuire D, Luther
RR (2000) Ziconotide, a new N-type calcium channel blocker, administered
intrathecally for acute postoperative pain. Regional Anesthesia and Pain
Medicine 25:274-278

2.         Moskovitz B, Bolkier M, Ginesin Y,
Levin DR, Rosenberg B (1986) Epidural morphine: a new approach to combined
anesthesia and analgesia in urological patients. European Urology,

3.         Myles PS, Peyton P, Silbert B, Hunt J,
Rigg JRA, Sessler DI (2011) Perioperative epidural analgesia for major
abdominal surgery for cancer and recurrence-free survival: Randomised trial.
BMJ 342:746

4.         Pfluke JM, Parker M, Stauffer JA,
Paetau AA, Bowers SP, Asbun HJ, Smith CD (2011) Laparoscopic surgery performed
through a single incision: A systematic review of the current literature.
Journal of the American College of Surgeons 212:113-118

5.         Rottichieri D (1972) A controlled study
of a new analgesic (Z867) in post-operative urological patients. International
journal of clinical pharmacology, therapy and toxicology 6:310-314

6.         Soumpasis I, Kanakoudis F, Vretzakis G,
Arnaoutoglou E, Stamatiou G, Iatrou C (2010) Deep anaesthesia reduces
postoperative analgesic requirements after major urological procedures.
European Journal of Anaesthesiology 27:801-806

7.         White PF (1990) Subcutaneous-PCA: An
alternative to IV-PCA for postoperative pain management. Clinical Journal of
Pain 6:297-300

E6: Full text is not available
(including studies only published as abstracts)

1.         Bianchi M, Allara A, Panerai AE (1993)
A randomized, placebo-controlled study on the efficacy of ketorolac
tromethamine in the prevention of postoperative pain. European Journal of Pain

2.         De S, Bell D, Launcelott G, Bailly G,
Bagnell S, Lawen J, Norman R, Rendon RA (2011) Surgeon-administered regional anesthesia,
using the transversus abdominal plane (TAP) block during radical retropubic
prostatectomy (RRP): A randomized double blinded, controlled trial. Journal of
Urology 185:e253

3.         Finnerty O, Carney J, Laffey J,
McDonnell J (2011) A comparison of continuous epidural based versus transversus
abdominis plane (TAP) block based regimens in patients undergoing retropubic
prostatectomy. Anesthesia and Analgesia 112

4.         Kitayama M, Hashimoto H, Kudo T, Takada
N, Wada M, Hirota K (2010) Plasma concentration of ropivacaine after
ultrasound-guided transversus abdominis plane block for open retropubic
prostatectomy. British Journal of Anaesthesia 105:712P-713P

5.         Kommu S, Crosby A, Hashim Z, Golash A,
Luscombe C, Augustine A (2009) Role of Ultrasound Guided Transversus Abdominis
Plane (USTAP) Block in analgesic supplementation for Laparoscopic Radical
Prostatectomy-preliminary findings. Journal of Endourology 23:A3-A4

6.         Smaldone M, Chelly J, Nelson J (2010) A
prospective, randomized, double-blind, placebo controlled trial of multimodal
anesthesia compared to patient controlled opioid anesthesia in patients
undergoing radical prostatectomy. Journal of Urology 183:e605

7.         Tetzlaff D, Koss W, Oldenburger A,
Glaser T, Werning P, Hammerer P (2009) Pain after Radical Prostatectomy (RP) in
Patients with Peridural Catheter (PDC) and Patient-Controlled Analgesia Pumps
(PCA). Urology 74:S274-S275

E7: Full text is not published in

1.         Cheng YD, Zhou ZQ, Chen WP, Hu SJ, Guo
MZ, Lin DD (2003) Application of morphine analgesia after prostatectomy.
Journal of Chinese Physician,

2.         Dimirel CB, Kati I, Cem Tuncer Y,
Huseyinoglu UA, Silay E (2001) Anaesthetic and hemodynamic effects of
continuous spinal anaesthesia versus single dose spinal anaesthesia in elderly
patients. Turk Anesteziyoloji Ve Reanimasyon,

multiple publication

1.         Shir Y, Frank SM, Brendler CB, Raja SN
(1994) Postoperative morbidity is similar in patients anesthetized with
epidural and general anesthesia for radical prostatectomy. Urology,